I was wondering if there is any advantage in the conversion process from Word to Kindle format if I create the Word document with any one particular page size? Would an original manuscript, created as a Word Document, with pages sized to 6" x 9" garner the same results as manuscript created with an 8" x 10" layout?
Try it out. If you download the calibre ebook management program, you can convert either format to kindle format. Then transfer it to your kindle either directly or by email and see what it looks like.