I have a non-fiction book that is ready for publishing, and I am weighing between whether to self-publish via modern methods made available by the internet, or go the more traditional route of searching for some kind of agency or publisher. My current feeling on the matter is that the pros of traditional representation no longer sufficiently outshine self-publishing. I realize this is a contentious issue, though, so I am only trying to express what I think might work best for me, not trying to make any general pronouncements.
However, even though self publishing seem the best way forward for me at this stage, I am always adverse to closing any doors, and I wonder if doors do get closed by self publishing.
I am considering using the suite of Amazon services for eBook, Print on Demand, and audiobook distribution. If I do this, then, at some time in the future, if the opportunity to work with a publisher should arise, or if I become motivated to try and find representation, does the fact that I have already made my book available sour the desire for any agent or publisher to want to take my book further?